Immunohistochemistry Kits and Reagents
ACROBiosystems Human Claudin-18.1 Protein, His-Flag Tag (Detergent), 100 μg
Recombinant human Claudin-18.1 is an integral membrane protein provided as a detergent-solubilized, tagged protein for biochemical and binding studies. It is expressed in baculovirus-insect cells and formulated to preserve membrane protein solubility and activity.
- Expressed in baculovirus-insect cells.
- Contains amino acids Met 1-Ala 200 (Accession # P56856-1).
- Includes an N-terminal polyhistidine tag and a C-terminal Flag tag.
- Supplied in a detergent buffer containing DDM and CHS to maintain membrane protein solubility.
- Provided as a 0.2 μm filtered solution with glycerol as protectant.
- Not suitable for cell-based experiments due to detergent cytotoxicity.
- Supplied amount: 100 μg.
- Purity greater than 90% as determined by SDS-PAGE.
- Calculated molecular weight: 40.9 kDa.
Immudex Klickmer dextran backbone reagent, 200 μL, 160 nM concentration, mono-biotinylated ligands, ~40 acceptor sites, for research use only
Klickmer dextran backbone reagent, 200 μL, 160 nM concentration, mono-biotinylated ligands, ~40 acceptor sites, for research use only
ABclonal Technology KO Validated Claudin 1
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet with complementary grooves in the inwardly facing extracytoplasmic leaflet The protein encoded by this gene a member of the claudin family is an integral membrane protein and a component of tight junction strands Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome
Biocare Medical, LLC Ki-67 + Caspase-3 Antibody - Predilute, 6.0 ml
Ki-67 Caspase-3 can provide information on cell death vs. cell proliferation in the same tissue section. The Ki-67 nuclear antigen is associated with cell proliferation and is used to grade proliferation rates of tumors. Ki-67 is found throughout the cell cycle that includes the G1, S, G2, and M phases; but not the G0 phase. Apoptosis has gained central importance in the study of many biological processes, including neoplasia, neurodegenerative diseases, and development. Cleaved caspase-3 detects endogenous levels of the large fragment of activated caspase-3, a protease that mediates apoptosis. Caspase-3 does not cross react with other cleaved caspases.
ABclonal Technology Phospho-p38 MAPK-T180/Y182
The protein encoded by this gene is a member of the MAP kinase family MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation differentiation transcription regulation and development This kinase is activated by various environmental stresses and proinflammatory cytokines The activation requires its phosphorylation by MAP kinase kinases (MKKs) or its autophosphorylation triggered by the interaction of MAP3K7IP1 TAB1 protein with this kinase The substrates of this kinase include transcription regulator ATF2 MEF2C and MAX cell cycle regulator CDC25B and tumor suppressor p53 which suggest the roles of this kinase in stress related transcription and cell cycle regulation as well as in genotoxic stress response Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported
Abcam DoubleStain IHC Kit: M&R on human tissue (HRP/Green & AP/Red), 18ML
Abcam's DoubleStain IHC Kit: M&R on human tissue (HRP/Green & AP/Red) (ab210061) is designed to detect two distinct antigens on human tissue or cell samples using a simplified protocol with user-supplied mouse and rabbit antibodies.
The product is subject to the following: Abcam Restricted Use Statement
Abcam TripleStain IHC Kit: R&R&M on human tissue (DAB, AP/Red & Green/HRP), 6ML
Abcam's TripleStain IHC Kit (ab183288) is designed to be used with one mouse and two rabbit primary antibodies, supplied by the user, to detect three distinct antigens on human tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
Biocare Medical, LLC CD8 Antibody - Concentrate, 1.0 ml
CD8 rabbit antibody is a T-cell subset found in cortical thymocytes, T-cells and natural killer (NK) cells. CD8 rabbit antibody stains cortical thymocytes (70-80%), T-cells (25-35% of mature peripheral T-cells) and NK cells (30%). Studies have shown that CD8 is expressed more frequently in non-common type anaplastic lymphoma kinase positive anaplastic large cell lymphomas compared to the common form. The CD4:CD8 ratio may be helpful in distinguishing mycosis fungoides from its inflammatory mimics or as an aid in determining clinical outcome in cervical carcinoma. CD8 may be used in panels with CD3, CD4, CD57 and TIA-1.
ABclonal Technology Phospho-SMO-S616 Rabbit pAb
The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex.
Abcam DoubleStain IHC Kit: G&M on human tissue (Green/HRP & AP/Red), 6ML
Abcam's DoubleStain IHC kit (ab183272) is designed to use with user supplied goat and mouse antibodies to detect two distinct antigens on human tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology MAP2 Rabbit mAb
This gene encodes a protein that belongs to the microtubule-associated protein family The proteins of this family are thought to be involved in microtubule assembly which is an essential step in neurogenesis The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites implicating a role in determining and stabilizing dentritic shape during neuron development A number of alternatively spliced variants encoding distinct isoforms have been described
Active Motif MAXwash™ Washing Medium
MAXwash Washing Medium is a proprietary formulation designed and optimized to eliminate non-specific primary and secondary antibody binding. It has been tested and proven effective at eliminating off-target antibody binding in immunofluorescence assays.
Abcam DoubleStain CL IHC Kit: G&Rt on human/mouse tissue (HRP/Green & AP/Red), 60ML
Abcam's Doublestain IHC Kit (ab183282) is designed to be used with user supplied goat and rat primary antibodies to detect two distinct antigens on human or mouse tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
Revvity Health Sciences Inc AlphaLISA SureFire Ultra Multiplex Human Phospho-STAT6 (Tyr641 & total) Detection Kit, 50,000 Assay Points
AlphaLISA SureFire Ultra Multiplex Human Phospho-STAT6 (Tyr641 & total) Detection Kit, 50,000 Assay Points
ABclonal Technology Claudin 5 Rabbit mAb
This gene encodes a member of the claudin family Claudins are integral membrane proteins and components of tight junction strands Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets Mutations in this gene have been found in patients with velocardiofacial syndrome Alternative splicing results in multiple transcript variants encoding distinct isoforms